PGIMER Breakthrough in Celphos Poisoning Treatment

Doctors at the India===Postgraduate Institute of Medical Education and Research (PGIMER) in Chandigarh, India, have reported a major breakthrough in the treatment of aluminium phosphide poisoning, commonly known as Celphos. This is the first clinical study to demonstrate the effectiveness of intravenous lipid emulsion as a life-saving therapy for this highly fatal condition. The findings, published in the European Review of Medical and Pharmacological Sciences, show that patients receiving this treatment experienced a marked reduction in mortality, faster correction of metabolic acidosis, and improved hemodynamic stability. The study was guided by Sanjay Jain and led by Mandip Singh Bhatia, with Saurabh Chandrabhan Sharda as co-investigator. The research was funded by PGIMER's Medical Education and Research Cell. A key advantage of this novel treatment is its practicality, being inexpensive, widely available, and already stocked in most hospitals across India, including rural areas where Celphos poisoning is most prevalent. This development is particularly significant for agricultural states such as India===Punjab, India===Haryana, and India===Uttar Pradesh, which bear the maximum disease burden due to the widespread use of aluminium phosphide as a grain preservative.