Autism Subtypes Discovered by IIT, Child Mind

An international research team, co-led by the Istituto Italiano di Tecnologia>>> and the Child Mind Institute>>>, has identified two distinct subtypes of autism based on brain connectivity patterns: 'hyperconnectivity' and 'hypoconnectivity'. The study, coordinated by Dr. Alessandro Gozzi>>> and Dr. Adriana Di Martino>>>, analyzed functional connectivity in mouse models and human brain scans, linking these patterns to specific molecular underpinnings like synaptic and immune-related pathways. This discovery, published in Alto Neuroscience>>>, provides a biological foundation for precision medicine approaches in autism, moving beyond behavioral assessments to more targeted care. The research was supported by various organizations including the Simons Foundation>>>, Australia — Australian Research Council>>>, Brain & Behavior Research Foundation>>>, Fondazione Telethon>>>, and the United States — National Institute of Mental Health>>>.